Background: Salmonella enterica subsp. enterica serovar Agama (antigenic formula 4,12:i:1,6) is a serovar of the O:4 (B) serogroup. In 1956, serovar Agama was identified as a new serotype of Salmonella enterica, isolated from the feces of the agama lizard (Agama agama) in Nigeria. The first travel-related case of salmonellosis caused by serovar Agama involved a tourist who had visited Gabon in Central Africa. Serovar Agama has been reported to cause neonatal meningitis and septicaemia.
NCBI PD link for serovar Agama: https://www.ncbi.nlm.nih.gov/pathogens/isolates/#(taxgroup_name:%22Salmonella%20enterica%22)%20AND%20computed_types:(%22serotype=Agama%22)
Genetic characteristics: Serovar Agama has been found to be polyphyletic with one lineage identified and one stand-alone singleton that does not cluster with any other Salmonella Agama isolates. In a Nigerian study, serovar Agama isolated from poultry farms exhibited resistance to ampicillin, cefotaxime and ceftazidime.
Animal reservoir: Serovar Agama was found in lizards, chicken, cattle, badgers, and pigs.
Geographical distribution: Serovar Agama has been reported in the US, Nigeria, and Europe such as the UK, and France.
Human outbreaks: There have been no recent human outbreaks linked to this serovar.
Border rejections:
Year | Exporting country | Importing country | Associated source | Product category |
| 2019 | Nigeria | Germany | Sesame seeds | Nuts, nut products and seeds |
Recalls: There have been no recent recalls linked to this serovar.
Relevant links:
- https://www.nature.com/articles/179164b0
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2738453/
- https://pubmed.ncbi.nlm.nih.gov/26255922/
- https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1547190/full
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6556926/
- https://pubmed.ncbi.nlm.nih.gov/16311384/
- https://www.sciencedirect.com/science/article/abs/pii/S0007193517339969
- https://webgate.ec.europa.eu/rasff-window/portal/index.cfm?event=notificationDetail&NOTIF_REFERENCE=2019.0632