Salmonella Oranienburg

Background: Salmonella enterica subsp. enterica serovar Oranienburg (antigenic formula 6,7,14:m,t:[z₅₇]) is a serovar of the O:7 (C₁) serogroup. Serovar Oranienburg was first isolated from a child with gastroenteritis, a resident of a Children's Home in Oranienburg near Berlin, Germany in 1930. Serovar Oranienburg ranked as the 10th and 15th most Salmonella prevalent serovar in North and Latin America, respectively. In 2003, serovar Oranienburg was the nineth most common Salmonella serovar causing human salmonellosis. Serovar Oranienburg was reported to cause haemorrhagic cystitis in an immunocompetent young male in Australia. In Japan, this serovar was documented to be bacteremia-related. 

NCBI PD link for serovar Oranienburg: https://www.ncbi.nlm.nih.gov/pathogens/isolates/#(taxgroup_name:%22Salmonella%20enterica%22)%20AND%20computed_types:(%22serotype=Oranienburg%22)

Genetic characteristics: In Argentina, an strain encoding extended-spectrum β-lactamases was reported in a pediatric hospital.

Animal reservoir: Chicken may be a potential reservoir for serovar Oranienburg. This serovar was also isolated from other animals including bovine, equine, porcine, canine, and wild animals.

Geographical distribution: While Serovar Oranienburg has been reported globally, it occurs most frequently in North and Latin America.

Human outbreaks: Multiple human outbreaks linked to serovar Oranienburg have been reported. They were associated with a variety of food. Below are examples. 

¹ There were 407, 190 cases reported in US and Canada, respectively. Salmonella Soahanina, Sundsvall, Oranienburg, and Newport were involved.

² While the total case number was not reported, 439 confirmed cases were documented in Germany.

Animal outbreaks:

¹ The herd size was 604 (Salmonella Oranienburg prevalence: 27.8%). 

Border rejections: Multiple border rejections linked to serovar Oranienburg have been reported. The majority of them were linked to black pepper imported from Brazil to Germany. Below are examples.

¹ Salmonella Oranienburg and Javiana were found.

² Salmonella Morehead and Oranienburg were found.

Recalls: Multiple recalls linked to serovar Oranienburg have been reported. Below are some examples. 

¹ Root cause analysis identified possible cross-contamination from a positive Salmonella sample as the source of error.

² This recall was caused by a national outbreak described above. Whole melons from Crown Jewels Produce were recalled. 

³ This recall was caused by a multistate outbreak described above. ProSource Produce, LLC and Keeler Family Farms of Deming issued recalls. 

⁴ This recall was caused by an international outbreak described above. 

Relevant links:

1. https://journals.asm.org/doi/pdf/10.1128/jb.32.3.259-263.1936
2. https://web.archive.org/web/20050520232026/http://www.cdc.gov/ncidod/dbmd/phlisdata/salmtab/2003/SalmonellaTable1_2003.pdf
3. https://pmc.ncbi.nlm.nih.gov/articles/PMC5610707/
4. https://pmc.ncbi.nlm.nih.gov/articles/PMC9846185/
5. https://militaryhealth.bmj.com/content/112/4/211
6. https://www.eggindustrycenter.org/soranienburg#:~:text=Specific%20animal%20species%20that%20can,salad%20and%20most%20recently%20eggs.
7. https://pubmed.ncbi.nlm.nih.gov/21492021/
8. https://marlerclark.com/salmonella-cantaloupe-outbreak-hits-43-in-15-states
9. https://www.fda.gov/food/outbreaks-foodborne-illness/outbreak-investigation-salmonella-oranienburg-whole-fresh-onions-october-2021
10. https://archive.cdc.gov/www_cdc_gov/salmonella/oranienburg-10-16/index.html
11. https://www.cdc.gov/mmWR/preview/mmwrhtml/mm5639a3.htm
12. https://www1.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi3002f.htm
13. https://www.researchgate.net/publication/6934802_Outbreak_of_Salmonella_oranienburg_infection_in_Japan
14. https://web.archive.org/web/20090710153211/https://www.fda.gov/Food/ScienceResearch/ResearchAreas/SafePracticesforFoodProcesses/ucm091270.htm
15. https://www1.health.gov.au/internet/main/publishing.nsf/Content/cda-pubs-cdi-1998-cdi2208-cdi2208d.htm
16. https://www.cdc.gov/mmwr/preview/mmwrhtml/00001205.htm
17. https://www.liebertpub.com/doi/10.1089/fpd.2010.0551?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
18. https://webgate.ec.europa.eu/rasff-window/screen/notification/524928
19. https://webgate.ec.europa.eu/rasff-window/screen/notification/524019
20. https://webgate.ec.europa.eu/rasff-window/screen/notification/418605
21. https://webgate.ec.europa.eu/rasff-window/screen/notification/416416
22. https://www.foodsafetynews.com/2024/07/lab-error-behind-false-salmonella-finding-in-finland/
23. https://www.marlerblog.com/case-news/more-cantaloupe-recalled-due-to-salmonella-oranienburg-and-sundsvall-outbreak/
24. https://www.fda.gov/safety/major-product-recalls/2021-recalls-food-products-associated-onions-prosource-produce-llc-and-keeler-family-farms-due
25. https://pmc.ncbi.nlm.nih.gov/articles/PMC552305/

1. http://link.springer.com/article/10.1186%2F1471-2334-5-7
2. http://www.ncbi.nlm.nih.gov/pubmed/16850895
3. http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5639a3.htm
4. http://www.ncbi.nlm.nih.gov/pubmed/23425126
5. http://www.ncbi.nlm.nih.gov/pubmed/20464138
6. http://www.ncbi.nlm.nih.gov/pubmed/20939741
7. http://www.fda.gov/Food/RecallsOutbreaksEmergencies/Outbreaks/ucm523017.htm
8. https://doi.org/10.1111/zph.13174