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Created by
Brad Yang, last updated on Mar 23, 2025
1 minute read
Background: Salmonella enterica subsp. houtenae serovar 50:z4,z23:- (antigenic formula: 50:z4,z23:-) is a serovar of the O:50 (Z) serogroup. This serovar is also known as serovar IV Flint. Serovar 50:z4,z23: was first isolated from three cultures in 1964 in the US: two were recovered from the stools of hospitalized male siblings, aged 10 and 27 months, both suffering from severe gastroenteritis at the time of isolation, and the third strain was isolated from a bird snake. This serovar was previously reported to cause systemic salmonellosis in a Florida manatee (Trichechus manatus latirostris). More specifically, necropsy and histopathological analysis revealed a chronic systemic bacterial infection affecting the renal, respiratory, lymphatic, and skeletal systems.
NCBI PD link for serovar IV 50:z4,z23:-: https://www.ncbi.nlm.nih.gov/pathogens/isolates/#(taxgroup_name:%22Salmonella%20enterica%22)%20AND%20computed_types:(%22serotype=IV%2050:z4,z23:-%22)
Genetic characteristics:
Animal reservoir:
Geographical distribution: Based on the NCBI PD metadata, serovar IV 50:z4,z23:- has only been reported in the US, Canada, Brazil, the UK, Germany, and Taiwan.
Human outbreaks: Unclear, but there have been no recent human outbreaks linked to this serovar.
Border rejections: There have been no recent border rejections linked to this serovar.
Recalls: There have been no recent recalls linked to this serovar.
Relevant links: