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Genetic characteristics: den Bakker et al. and Miller et al. suggested that serovar Mississippi was likely to be polyphyletic.   Cheng et al. phylogenetic analysis of 364 S. Mississippi isolates from Australia, the UK, and US revealed geographic clustering, with U.S. (subclade Ai) and Australian (subclade Aii) isolates forming distinct groups within clade A, while clade B predominated in the UK. Genetic divergence within clades was driven by mobile elements carrying virulence factors: clade A variations arose from prophage differences (i.e., Entero_mEp460, Gifsy-2, Salmon_118970_sal3, and Salmon_vB_SosS_Oslo), whereas clade B diversity stemmed from acquisition of a 47.1-kb integrative conjugative element (ICE).

Animal reservoir: Unknown, but according to the metadata from NCBI PD, serovar Mississippi was isolated from wild animals such as turtles, and birds (Porphyrio hochstetteri). 

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