Issues with Round trip editing on Macs:

• For those using Office 2011 on Macs, it was possible to be able to drag and drop from Chemdraw into Word 2011 and drag and drop the image back into Chemdraw for editing. This is no longer the case for Office 2016.
• Dragging and dropping from ChemDraw 15.1 to Word 2016 will paste an image into the Word document but the image will NOT be editable
• Copying(⌘+C) and Pasting (⌘+V) will only paste text into Word(2016)
• IMPORTANT: Opening a old Office 2011 file in Office 2016 and resaving it will not affect the images already in the document (you can drag them into Chemdraw for editing). However, anything dragged into Office 2016 will still not be editable

Workarounds:

• Use paste as PDF instead of dragging and dropping. Copy the image from ChemDraw(⌘+C) and Paste it into Word 2016 using ⌘+Control+V instead of ⌘+V.