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Genetic characteristics: Serovar Worthington has been found to be polyphyletic with 1 one lineage identified and 1 one stand-alone singleton that does not cluster with any other Salmonella Worthington isolatesSalmonella Worthington isolates from preharvest turkey production sources pose both virulence and persistence by carrying virulence genes, such as invA, aceK, and sopB, along with resistance to many antibiotics (tetracycline, erythromycin, bacitracin, novobiocin, and rifampin). Salmonella Worthington has been reported as having acquired the third-generation cephalosporin resistance plasmid (blaDHA-1-carrying IncFII plasmid) from Citrobacter amalonaticus

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Human outbreaks: Several human outbreaks have been associated with S. Worthington. Below are some examples.

YearLocationAssociated SourcesourceNumber of Casescases
2012US-multistateMangoes16
2005FranceMilk powder49
2000IndiaNo source or carrier identified16
1975Hong KongTubing system of a suction apparatus18
1955IndonesiaArtificial feeding1154

1 Because of limitation of serological procedure at that time, this outbreak might be caused by pathogenic E. coli or Salmonella Worthington or both organisms

Border Rejectionsrejections: One case of border rejections associated with serovar Worthington was reported.

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1 This recall was caused by a multistate outbreak.  Daniella brand mangoes grown in Mexico were recalled.

Relevant links and references:1.

  1. https://www.jstor.org/stable/3859636?seq=3

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  1. https://academic.oup.com/trstmh/article/103/4/390/1918003?login=true

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  1. https://www.proquest.com/docview/304631473?pq-origsite=gscholar&fromopenview=true&sourcetype=Dissertations%20&%20Theses

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  1. https://www.sciencedirect.com/science/article/pii/S0168160503003301?via%3Dihub#BIB20

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  1. https://www.foodsafetynews.com/2012/10/after-salmonella-outbreaks-growers-are-told-mangoes-are-high-risk-fruit/
  2. https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2025.1547190/full