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NCBI PD link for serovar London: https://www.ncbi.nlm.nih.gov/pathogens/isolates/#(taxgroup_name:%22Salmonella%20enterica%22)%20AND%20computed_types:(%22serotype=London%22)
Genetic characteristics: Serovar London has been found to be polyphyletic with two lineages identified. In a nosocomial outbreak associated with serovar London, Yong et al. identified the CTX-M-14-type extended-spectrum β-lactamase-producing strains. All these outbreak strains were multidrug resistant (MDR), while the other London strains reported were susceptible to multiple antibiotics, including ampicillin, suggesting the susceptible clone retained the resistance. MDR serovar London carrying blaNDM-1 located on an IncA/C2 plasmid was reported in Singapore. A Chinese study analyzed a total of 88 representative isolates from human and food sources in Zhejiang Province, China, during 2016–2021 and revealed that all serovar London isolates wereidentified as ST155 (n = 62) and grouped into two divergent clusters. Compared to serovar Kentucky isolates included in this study, three virulence genes involved in Salmonella attachment were uniquely associated with serovar London isolates. Doxycycline resistance was the most common (74.2%, n = 46) in serovar London isolates, with tetracycline (71%, n = 44), ampicillin (64.5%, n = 40), and gentamicin (56.5%, n = 35) resistance also observed at high frequencies.
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