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NCBI PD link for serovar Saintpaul: https://www.ncbi.nlm.nih.gov/pathogens/isolates/#(taxgroup_name:%22Salmonella%20enterica%22)%20AND%20computed_types:(%22serotype=Saintpaul%22)
Genetic characteristics: Chen et al. found that serovar Saintpaul appeared to be polyphyletic with four distinct phylogenetic groups identified. Within serovar Saintpaul, the comparative genomic analysis revealed 384 and 619 genes enriched in isolates from 5 human-associated (HA) and 4 non-human-associated (NHA) SNP clusters, respectively, that showed the strongest association with their isolation sources. This included five known HA-linked virulence genes located on Gifsy-1/Gifsy-2 prophages. Additionally, premature stop codons were more prevalent in 3 HA and 7 NHA genes. Cell culture experiments with representative strains from 4 HA and 3 NHA clusters found no increased invasion or intracellular survival capability in HA SNP clusters. However, the presence of sodCI (encoding a superoxide dismutase)—detected in 4 HA and 1 NHA clusters—correlated with enhanced survival in macrophage-like cells.
Animal reservoir: Unknown, but turkey and swine are likely to be reservoirs for serovar Saintpaul.
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- https://www.jstor.org/stable/30092155?seq=2
- https://journals.asm.org/doi/10.1128/msphere.00730-21
- https://pmc.ncbi.nlm.nih.gov/articles/PMC2876473/
- https://pmc.ncbi.nlm.nih.gov/articles/PMC11942379/
- https://pubmed.ncbi.nlm.nih.gov/8774669/
- https://www.cdc.gov/salmonella/outbreaks/index.html
- https://www.clinicalcasereportsint.com/open-access/top-10-salmonella-serovars-associated-with-human-salmonellosis-in-brazil-2011-2020-8688.pdf
- https://www1.health.gov.au/internet/main/publishing.nsf/Content/cda-cdi4101k.htm
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