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Genetic characteristics: In a nosocomial outbreak associated with serovar London, Yong et al. identified the CTX-M-14-type extended-spectrum β-lactamase-producing strains. All these outbreak strains were multidrug resistant (MDR), while the other London strains reported were susceptible to multiple antibiotics, including ampicillin, suggesting the susceptible clone retained the resistance. . MDR serovar London carrying blaNDM-1 located on an IncA/C2 plasmid was reported in Singapore. A Chinese study analyzed a total of 88 representative isolates from human and food sources in Zhejiang Province, China, during 2016–2021 and revealed that
Animal reservoir:
Geographical distribution: According to the metadata from NCBI PD, serovar London has been reported worldwide but mainly in US, China, and UK.
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