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Background: Salmonella enterica subsp. enterica serovar Dublin (antigenic formula 1,9,12[Vi]:g,p:-) is a serovar of the O:9 (D₁) serogroup. Serovar Dublin is a serovar adapted to cattle, which is the primary host, but it can also infect and cause disease in different hosts, including humans. In cattle, serovar Dublin causes acute and subclinical disease; symptoms of salmonellosis in cattle include: fever, diarrhea, abortions, respiratory signs (especially in calves), and systemic disease, thus making serovar Dublin an important economic concern in the bovine industry. Serovar Dublin is a zoonosis that causes one of the highest rates of systemic disease among all non-typhoidal salmonellosis cases in humans. In Similar to Salmonella Choleraesuis, serovar Dublin infections in humans were linked to a higher incidence of bacteremia (91%), metastatic infections (30%), and mortality rates (26%) compared to other non-typhoidal Salmonella serovars. In the U.S., S. Dublin is the second most common Salmonella serovar among clinical non-human sources.

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Genetic characteristics: In 2012, the Animal Health Diagnostic Center at Cornell University published an animal health advisory that indicated an increase in the isolation of multidrug resistant strains of serovar Dublin in New York. Among ceftriaxone-resistant Salmonella isolates reported by the National Antimicrobial Resistance Monitoring System (NARMS), serovar Dublin represents the 40.8% and 2.9% of isolates from cattle and humans, respectively.

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